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August 26, 1905


JAMA. 1905;XLV(9):600-606. doi:10.1001/jama.1905.52510090022001e

PREFACE.  The uniform satisfaction given by the iodin catgut prepared after the method of Claudius,1 which has been used by Dr. Nicholas Senn in his clinical work, led him to employ a solution of iodin for irrigation in infected wounds and also for hand sterilization. The results obtained demonstrated, clinically, the marked potency of iodin in solution as an antiseptic. Its continued use for several years has shown it to be far superior to any antiseptic previously employed.In order to determine the absolute value of this solution, a series of experiments have been carried out on a number of different micro-organisms in vitro. A sufficient number of different organisms and a great number of tubes have been used. Therefore one is justified in assuming that the conclusions arrived at from a careful study of the series of experiments represent as nearly as possible the position of iodin in

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