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August 26, 1905


JAMA. 1905;XLV(9):632. doi:10.1001/jama.1905.02510090054004

In his recent address before the American Chemical Society at its Buffalo meeting, Professor J. H. Long1 discusses briefly some of the most important recent advances in physiologic chemistry. While the work referred to may be familiar to many, nevertheless an outline of Professor Long's address may not be without interest because it should give us a fairly definite idea of what the actual workers in this field, the physiologic chemists, themselves consider the most important lines of advance.

The first problem discussed is that of protein in nutrition, a much debated question ever since the beginning of physiologic chemistry. Liebig held that the protein substances were built up into tissues and that the oxidation of these was the sole source of muscular energy. In 1866, however, Fick and Wislicenus showed that protein combustion was far too little to account for the muscular work done in an ascent of