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Article
April 27, 1912

THE INHERITANCE OF THE NEUROPATHIC CONSTITUTION

Author Affiliations

KINGS PARK, N. Y.

JAMA. 1912;LVIII(17):1266-1269. doi:10.1001/jama.1912.04260040282006
Abstract

I. MENDEL'S THEORY AND NEUROPATHIC HEREDITY  The application of Mendel's theory in recent studies of heredity in feeble-mindedness,1 epilepsy,2 insanity,3 and other neuropathic conditions,4 has furnished results which seem to justify the assumption that the full development and normal function of the mental faculties are dependent on the presence of a special determiner in the germ-plasm.An individual may inherit this determiner from both parents, or from only one, or he may fail to inherit it from either parent. In the first case we would have an instance of duplex inheritance, in the second, one of simplex inheritance, and in the last, one of nulliplex inheritance.In cases of duplex inheritance—cases, that is to say, in which the indivisual inherits the determiner for complete mental development from both parents—we find no abnormal mental traits, but, on the contrary, a most striking stability and a resistance to

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