The similarity which exists between general paralysis of the insane and tabes dorsalis has been noted and commented on since shortly after Westphal accurately described the latter disease. The concurrence of the two diseases is relatively so common, the relation of both conditions to syphilis is so frequent, and the pathology of the two diseases so similar that one is tempted to assume that they represent different phases of the same fundamental condition. It is the French school of physicians who have most ardently supported the view that unity between the two diseases exists, though some German observers, notably Schaffer, strongly support them. There are certainly many points in favor of such a view. According to Nageotte, two-thirds of the cases of general paralysis are accompanied by tabes; an individual may start with the latter disease, then mental symptoms may set in and the picture change to that of general
THE RELATIONSHIP BETWEEN GENERAL PARALYSIS AND TABES DORSALIS.. JAMA. 1905;XLV(10):720–721. doi:10.1001/jama.1905.02510100054009
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