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September 16, 1905


JAMA. 1905;XLV(12):856-857. doi:10.1001/jama.1905.02510120042008

In a recent issue we called attention to the catalytic nature of the intracellular ferments and referred more particularly to the work which has been done on the enzymes which accelerate proteolysis and autolysis. Just as interesting are the researches of ferment chemists concerning the influence of enzymes on the processes of oxidation which go on in living organisms. Since Lavoisier's time it has been known that the animal body possesses oxidizing properties; later studies went far toward localizing the oxidation processes in the cells (Hoppe-Seyler, Pflüger, Schmiedeberg); still later it was proved that the cells need not be intact to cause the oxidation, crushed cells and cell extracts being shown to be effective; finally, it has been demonstrated that the oxidizing processes in the cells are dependent on the presence in them of specific catalytic agents— the oxidizing enzymes or oxydases (Bertrand, Schoenbein, Jacquet, Schmiedeberg, Jacoby). A whole series