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May 25, 1912

The Caffein Investigations: A Further Reply

JAMA. 1912;LVIII(21):1620-1621. doi:10.1001/jama.1912.04260050294021

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To the Editor:  —My attention has been called to a letter from Dr. Wiley in The Journal (May 11, p. 1463), with reference to my recent experiments with caffein alkaloid. I desire to reply to some of the remarks and insinuations contained in that letter, and to thank you for your expression of confidence in the honesty of my work. The irrelevant parts of Dr. Wiley's letter, concerning my proper official title, my correct business address, etc., need no comment, since their connection with the influence of caffein is not clear. Moreover all of these facts are correctly stated on my monograph (The Influence of Caffein on Mental and Motor Efficiency, Arch. Psychol., Columbia University, No. 22, April, 1912), which appeared in April, some four weeks before the appearance of Dr. Wiley's letter.Moreover, in the preface of that monograph, a copy of which has been for some time in

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