It is exceedingly common for men of sedentary habits to use the week-end as a time in which to make up arrears of healthy, open-air exercise. Golf, tennis, boating, riding, etc., are indulged in vigorously. Such men are often surprised on their return to sedentary occupations, because, instead of feeling all keyed up for mental work, they find themselves dull, slow, logy and they may even suffer from headache. If, instead of returning to their usual habits, they keep up the active exercise, no such symptoms arise. A day of loafing as a break in a strenuous fishing or hunting trip is often a day of drowsiness, headache and bad temper. These results of the sudden cessation of active exercise are practically the same as the symptoms of a mild colonic intoxication though brought about in a different way, and one finds that they can be entirely avoided by the
BINNIE JF. SYMPTOMS OF COLONIC INTOXICATION. JAMA. 1912;LVIII(26):2011–2013. doi:10.1001/jama.1912.04260060364002
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