At the time I read Dr. Barton's article on "The Elimination of Hexamethylenamin by the Mucous Membrane of the Middle Ear,"1 together with report of a case of suppurative otitis media, I thought of the desirability of testing the effects of the drug in other conditions characterized by presence of a discharge; but at that time I was a student in a medical school and, lacking both the time and clinical opportunity to do so, soon forgot it.
On reading Dr. Vanderhoof's article,2 however, my interest in the subject was revived, and having this time both the time and the opportunity, I decided to test the efficiency of the drug, generally following Dr. Vanderhoof's suggestions as to the dosage and frequency of administration. I also decided to extend the scope of Dr. Vanderhoof's observations, including cases other than bronchitis. My clinical opportunity was very good. most of my
EISENBERG AA. THE USE OF HEXAMETHYLENAMIN IN THE AFFECTIONS OF THE UPPER RESPIRATORY TRACT. JAMA. 1912;LVIII(26):2032–2033. doi:10.1001/jama.1912.04260060385012
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