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January 3, 1914

PHTHISIOPHOBIA IN THE LIGHT OF RECENT DEVELOPMENTS IN TUBERCULOSIS INVESTIGATIONS

JAMA. 1914;LXII(1):45. doi:10.1001/jama.1914.02560260053026
Abstract

With the application of our growing knowledge of the immunologic reactions to tuberculosis, and especially the influence of allergy on the tuberculous process, have come new concepts and revivals or transformations of old ones. The studies of von Pirquet, Roemer and Hamburger, the workers in the laboratories at Saranac Lake, Calmette and others, have thrown a new light on the relation of allergy to tuberculosis and the nature of reinfection and superinfection. They show that what has been recognized clinically as a lowered resistance to tuberculosis, as after measles, influenza, etc., is undoubtedly associated with the condition of allergy of the person. Thus, von Pirquet found that in measles there may be a disappearance of an existing tuberculin sensitiveness during the height of the acute disease, with a return of the reaction later. Now since practically all persons become infected with tuberculosis in childhood, and become allergic to the tubercle

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