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October 14, 1905


JAMA. 1905;XLV(16):1170-1171. doi:10.1001/jama.1905.02510160044007

The occurrence of minor ailments of a hereditary character or with family grouping is of interest in connection with major diseases of a like familial distribution with which the minor ailments may possibly be interchangeable or represented in an abortive form. There are those who believe that the comparatively harmless migraine may thus be correlated with epilepsy, that periodic attacks of mental depression in healthy individuals correspond, in a sense, to the more severe periodic insanities, and that the rather rare hereditary or familial tremor may represent, in petto, as it were, Huntington's chorea.

Family tremor is perhaps less well known than many other family diseases, though Dana in this country was one of the first to describe it carefully. Occasional reference to the condition is found in the literature as early as the end of the eighteenth century, though the symptom-complex has been carefuly studied only in the last