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July 24, 1897


Author Affiliations

Assistant Director Pepper Laboratory of Clinical Medicine; Assistant Physician to the Hospital and Instructor in Clinical Medicine, University of Pennsylvania. PHILADELPHIA, PA.

JAMA. 1897;XXIX(4):162-166. doi:10.1001/jama.1897.02440300014001c

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It would be hopeless to attempt to review, even imperfectly, all of the questions of importance connected with the subject of anemia in the time at my disposal; but I believe it wisest to consider a few of the problems relating to the general conception of the nature of this disease or group of diseases, and to discuss briefly the varieties generally admitted to our nosology.

It is difficult to define anemia in a way satisfactory to the modern pathologic requirements. The older authors simplified the matter in conformity with the scope of their pathology, by defining it as bloodlessness, and by associating the clinical appearance of pallor with the disease anemia. Later, after the chemical studies of Andral and Gaveret. Becquerel and Rodier and Schmidt, names which must forever occupy a conspicuous place in the history of hematology, clearer conceptions of the exact nature of the disease seemed within

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