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Its control over the ciliary muscle.
—In 1881, soon after its introduction, I commenced the use of homatropin hydrobromate as a cycloplegic for the determination of refraction. At first it was used occasionally, then more frequently, and after a year or two for the majority of cases of ametropia encountered in private practice.It was known to be less powerful than the other drugs employed for the same purpose. On that account its results were always regarded with some doubt, and where there seemed to be any especial uncertainty as to the findings made with it, it was followed by the instillation of one of the stronger mydriatics. In 1886 I published (Medical News, July 24) the results obtained in these cases where the use of homatropin had been followed by one of the stronger mydriatics."In but fifteen out of the fifty-two eyes was there any difference between the
JACKSON E. THE VALUE OF HOMATROPIN IN THE DIAGNOSIS OF AMETROPIA. JAMA. 1896;XXVII(21):1095–1097. doi:10.1001/jama.1896.02430990019001f
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