This operation consists of extirpating an organ, with its vessels, of putting it in another region, and of uniting its vessels to a neighboring artery and vein. If the organ is replaced in the same animal from which it was removed, the operation is called an autotransplantation. If it is placed in another animal of the same species it is called a homotransplantation, while if it is placed in an animal of a different species, the operation is called a heterotransplantation.
The so-defined transplantation completely differs from the well-known experiments of subcutaneous or intraperitoneal grafts of small slices of organs.
The literature of the transplantation of organs is not extensive.In 1901-02 I began experimenting with the view of finding a method of substituting a sound organ for a diseased one, e. g., of treating Bright's disease by replacing the diseased kidney by a normal one, or myxedema by
CARREL A. THE TRANSPLANTATION OF ORGANS.A PRELIMINARY COMMUNICATION. JAMA. 1905;XLV(22):1645–1646. doi:10.1001/jama.1905.52510220031001i
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