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The study of the ductless glands seems to be just making its beginning. The thyroid presents an interesting example, but as yet our knowledge of this organ remains almost as unsatisfactory as complete ignorance. The absence of the thyroid determines a pathologic condition known as myxedema, its abnormal activity another condition known as exophthalmic goiter. The former disease has been successfully treated by the implantation of pieces of living thyroid or by feeding fresh or dried thyroid tissue, and the latter has in some cases been cured by the removal of the enlarged or vicious thyroid gland.
An analogous condition prevails in the case of the adrenal glands. When these glands are destroyed by tuberculosis, or by other diseases, a condition known as Addison's disease is instituted. This disease is characterized by a bronzing of the skin, a loss of strength and a rapid, small soft pulse. All the other
THE ADRENAL TUMORS GROWING OUT OF THE KIDNEY. JAMA. 1897;XXIX(7):344–345. doi:10.1001/jama.1897.02440330044008
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