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November 25, 1905


JAMA. 1905;XLV(22):1656. doi:10.1001/jama.1905.02510220042004

The art of diagnosis requires a knowledge not only of the main types of a given disease, but also of its atypical forms, the so-called formes frustes of French writers. In some diseases easy of recognition in their typical form, atypical forms are common and difficult of recognition, and of no disease is this more true than of paralysis agitans. According to Erb's observations, paralysis agitans presents itself in an atypical form in about 20 per cent, of all cases, and Oppenheim believes that this estimate is too low rather than too high. Under such circumstances, a knowledge of the atypical forms of this disease is a necessity, as the condition is not uncommon.

Oppenheim1 has recently expressed his views regarding this disease in a masterly paper in which he pays especial attention to the diagnosis of masked cases. Paralysis agitans without tremor, first described by Charcot in 1875,

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