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—A mistake in diagnosis is frequently made, even in pronounced cases. In the Howard Hospital a very marked case in all its characteristics had been treated, as long as a year, for chronic gastric catarrh as well as liver trouble instead. A knowledge of the clinical features of the disease is essential to diagnosis, a fact which should be better known to the profession. Within two years I have seen a case very similar to one of Dr. Anders. The patient was a woman who had been treated about two years for parenchymatous nephritis. The urinary changes were markedly pronounced, but at no time were there cardiac changes or edema, and it was only as a tentative treatment that thyroid was tried, not so much with the idea that there was a myxedematous complication. The result was eminently satisfactory, for the urine has been normal for a period
DISCUSSION ON PAPER OF DR. J. M. ANDERS OF PHILADELPHIA, "MYXEDEMA WITH REPORT OF TWO CASES.". JAMA. 1897;XXIX(8):385. doi:10.1001/jama.1897.02440340033002p
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