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In the term metabolism we mean to express the group of phenomena whereby organic beings transform foodstuffs into complex tissue elements, and convert complex substances into simple ones, in the production of energy; in other words the entire process of tissue building, which includes the proper throwing off of unused débris and the elimination of excretory matter, the complete scheme of nutrition, tissue making, production of energy and the elimination of waste matter.
After an individual has secured his growth, if no mistake has been made, we have an animal mechanism which, under proper conditions, should be good for seventy or eighty years of continued work. Any break in the continuity of this mechanism can safely be interpreted as due to an interruption in metabolism. This interruption may be and generally is at first a light one and if taken promptly may be easily corrected. If this be neglected and
LOVE IN. INTERRUPTIONS IN METABOLISM. JAMA. 1897;XXIX(9):423–424. doi:10.1001/jama.1897.02440350021001c
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