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This substitute for iodoform is offered to the profession because of the unpleasant odor, often irritating character and, last but not least, of the non-antiseptic properties of the latter. It is a well known fact that iodoform is not an antiseptic, so we must look forward to a preparation which will fulfil our wants. Bacteriologists have proven that cultures of pathologic and non-pathologic bacteria may be propagated on it. Shirmunski demonstrated the non-antiseptic properties of iodoform as follows: He added to a gelatin solution iodoform and sterilized water; this mixture again was poured into shallow dishes, allowed to evaporate, on which iodin was liberated, but nevertheless bacteria grew on this culture medium. He also experimented by mixing staphylococci and streptococci with iodoform, but after making culture from the mixture found that not only were the pus germs propagating, but also that bacteria which were originally found in the iodoform were
COHN AH. CARVACROL IODID. JAMA. 1897;XXIX(10):464–465. doi:10.1001/jama.1897.02440360008002a
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