[Skip to Navigation]
December 9, 1905


JAMA. 1905;XLV(24):1803-1804. doi:10.1001/jama.1905.02510240035005

Recent histologic and bacteriologic studies of the bone-marrow, not only in typhoid fever, but also in influenza, smallpox and other infectious diseases, have shown this tissue to be so frequently affected that it is remarkable that clinical symptoms on the part of the bones are not more often noted in such affections. That [ill]ey have been noted to some extent can not be denied, but that a general recognition of bone lesions as a result of infectious diseases has not yet taken place can be easily proved by a glance through recent medical literature. The lack of recognition of such lesions is probably due in the main to two reasons, one being that the pains which form so prominent a symptom of such cases are referred to the muscles or nerves, the other that these post-infectious bone lesions tend to heal spontaneously and without the formation of pus.

The lesion