Methods for the clinical determination of the quantity of dextrose in urine have never been very satisfactory. Practically the only method used to any extent is that which employs the Einhorn fermentation saccharimeter. This method is very inaccurate, errors resulting from differences in the activity of the yeast used and in the temperature at which the instrument is kept while fermentation is proceeding. Another disadvantage of the fermentation procedure is that several hours at least must elapse before a final reading can be made.
Recognizing the inadequacy of this method, I have attempted to devise a method for the colorimetric determination of dextrose in urine which is simple, fairly accurate and rapid. Several colorimetric methods for the determination of dextrose in urine have been described. Among these are the methods of Neitzel,1 Ruini,2 Järvinem3 and Dehn and Hartman.4
These methods, however, are hardly suitable for the
KLEINER SB. A CLINICAL METHOD FOR THE RAPID ESTIMATION OF THE QUANTITY OF DEXTROSE IN URINE. JAMA. 1914;LXII(17):1307–1308. doi:10.1001/jama.1914.02560420013006