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December 16, 1905

Acetozone Solutions.

JAMA. 1905;XLV(25):1892. doi:10.1001/jama.1905.02510250058018

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New Haven, Conn., Dec. 3, 1905.

To the Editor:  —I am anxious to learn if any one else has had any experience in the use of acetozone solutions for injection into the spinal canal after lumbar puncture in cerebrospinal meningitis. I have used it recently with apparently good results in two severe and protracted cases. In both these cases puncture had already been required to relieve urgent pressure symptoms, but, while successful in this respect, the procedure had been without effect on the temperature. After the acetozone injections this remained nearly normal. A weak solution (5 grains to quart) was used, the patients being aged 7 and 4 respectively. In the first case 30 c.c. of fluid were withdrawn and 15 c.c. of the acetozone solution injected; in the second case 35 c.c. were withdrawn and 15 c.c. injected. In the acute fulminating cases, in which death takes place before

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