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Since argyrism is a rare condition, a report of the following case, which came under my observation recently, may be of interest. We do not see the baneful effect of chronic silver poisoning, as did our forefathers, because we do not employ this metal internally so often as they did. There is nevertheless a danger to argyrism resulting from the prolonged use of the colloidal preparations of silver now in vogue, especially since the manufacturing houses advertise widely that these preparations are innocuous and vaunt their virtue to the skies.
The patient was a young woman sent to me by her physician, with the request that she be operated on. In his letter he said that she had been suffering for years from gastrointestinal troubles, which he attributed to gall-bladder obstruction. The most noticeable thing about the patient was her complexion, which had a dark bluish hue, with bright glistening
ANTONIO M. CRISPIN. ARGYRISM FOLLOWING THE USE OF COLLARGOL. JAMA. 1914;LXII(18):1394. doi:10.1001/jama.1914.02560430024010