This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.
The spirochete studied was obtained through the kindness of Dr. Norris of Bellevue Hospital, New York, who secured it from a case of relapsing fever by inoculating the blood into monkeys and white rats. The organism has been kept alive by successive passage through white rats for over two months. As a result of intraperitoneal injection the parasites appear in the blood in thirty-six to forty-eight hours after inoculation, disappear within the next twenty-four hours and do not reappear. The rats are then immune to subsequent inoculation. The disappearance of the spirochetes was shown to be due to the formation of anti-bodies. Spirochetal blood, when kept in vitro, retains its virulence for more than fifteen days.The blood of rats which have been given repeated injections of spirochetal blood exerts a most marked preventive and curative action. When injections of such blood are made, before inoculation with spirochetes,
NOVY FG, KNAPP RE. SPIROCHÆTE OBERMEIERI. JAMA. 1906;XLVI(2):116. doi:10.1001/jama.1906.62510290036001i
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: