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June 13, 1914

AN AID TO PROGNOSIS IN PULMONARY TUBERCULOSISA SIMPLE URINARY TEST: THE UROCHROMOGEN REACTION OF WEISZ

JAMA. 1914;LXII(24):1886-1888. doi:10.1001/jama.1914.02560490032010
Abstract

We think that all physicians who have had any considerable experience in the treatment of patients with pulmonary tuberculosis will agree that in many cases it is difficult to make an accurate prognosis. Will this patient recover? Will that patient succumb? These are questions that cannot always be answered correctly. Because of these facts, any test or procedure which will in the slightest degree assist in making more accurate prognoses, especially if simple and easily applied, demands careful attention. We have, therefore, felt justified in outlining our experience with Weisz' urochromogen reaction in the urine of patients sick with pulmonary tuberculosis.

For several years we have considered the presence of a diazo-reaction in the urine (if more than transient) as an unfavorable prognostic sign,1 but unfortunately the actual practical value of the diazo-reaction is limited, for its absence is not necessarily a favorable prognostic sign, many cases with a

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