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June 20, 1914

THE TRANSMISSION OF TYPHUS FEVER

JAMA. 1914;LXII(25):1966. doi:10.1001/jama.1914.02560500036009
Abstract

In September, 1909, Nicolle, Comte and Conseil1 reported the successful transmission of typhus fever from one monkey to two others by means of the bite of the body-louse (Pediculus vestimenti). In their report they showed that body-lice that had fed on an infected monkey were able to convey typhus fever some time between the first and the seventh day thereafter.

Independently of Nicolle and his co-workers, Anderson and Goldberger,2 in their studies on typhus fever in Mexico in November, 1909, reported two attempts to transmit Mexican typhus from man to the monkey by means of the bite of the body-louse. In one of their experiments the monkey showed a slight elevation of temperature eight days after the last exposure to the bites of the infected lice, but they stated that circumstances made it impossible to test the immunity of this animal. In view of later studies by them

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