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November 13, 1897


Author Affiliations


JAMA. 1897;XXIX(20):1001-1004. doi:10.1001/jama.1897.02440460021002f

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All intelligent therapeusis must necessarily have as a basis a correct understanding of the etiologic factors that enter into the morbid complexus which it is intended to combat. That there can be no rational, treatment of tuberculosis without a correct knowledge of its pathology is evident. On the other hand, it can not be claimed that the histogenesis and progress of the various elements of tubercle are thoroughly understood, although all admit that many facts bearing on it are well determined. One of these facts is, that a vegetable parasite, infective in its nature, is in some way causative. Whether, however, the bacillus tuberculosis of Koch is the fundamental primary cause of this morbid complexus is not so generally acknowledged.

Many eminent pathologists point out the fact that not only the minute tissue changes, which identify the tubercular processes, are virtually one and the same, but that these tissue changes

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