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In a recent report to the Michigan State Board of Health, Dr. Charles T. McClintock of Detroit, makes the statement that "inspection of the most important laboratories of Germany, France, Austria and Great Britain reveals the fact that the methods in use for the production of diphtheria antitoxic serum and vaccine are much the same everywhere," etc. While this statement is entirely correct in a general way, it carries with it the impression that if the same methods are used by the various manufacturers, one could make just as good a serum as another, an impression as dangerous as it is erroneous. It is only necessary to mention the great discrepancy that exists between many of our drugs of the same name in order to illustrate this point. Essentially the same methods are used by all our manufacturers in the production of fluid extracts, for example, and yet our markets
COX GW. THE PREPARATION AND TESTING OF DIPHTHERIA ANTITOXIN. JAMA. 1897;XXIX(23):1159–1160. doi:10.1001/jama.1897.02440490025001m
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