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February 13, 1904


JAMA. 1904;XLII(7):469-470. doi:10.1001/jama.1904.02490520059007

In a recent communication,1 Dreyer of Copenhagen reports certain experiments of therapeutic interest on the bactericidal action of erythrosin—one of the eosin stains—in connection with the Finsen light. He finds that the addition of a very small amount of erythrosin to the culture media of bacteria and infusoria causes a very much greater sensitiveness on their part to the yellow and green rays (which are otherwise comparatively ineffective), and that it acts not only directly on the organisms in the cultures, but through a thick layer of integument as well, in this way destroying the Bacillus prodigiosus in twenty minutes. He recommends the use of a one per thousand sterile solution of the Grübler erythrosin in normal salt solution, the injection to be made according to Schleich's method at the site of the disorder; the Finsen light application fifteen to twenty minutes in well-vascularized, and, for a shorter time,