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Fever of a malarial origin is an annual visitant, from August to the middle of October, of all that vast section comprised within the Southern Atlantic and Gulf States, and also of a large portion of the interior, comprising the Middle, Western and Southern States. The large number of cases occurring within the vast area comprised within these borders, the distress of mind and body, the loss of time by sickness, the additional expense incurred, the impairment of health and the greatest of earthly evils, the mortality resulting, combine to render this one of the most important and interesting subjects in our profession, and how successfully to prevent malarial infection and to correct it after it enters the human system, become questions of paramount importance.
While this subject has for years received the closest attention from scientific and practical minds, it never loses interest or grows trite and in all
BROWN B. THE AUTUMNAL FEVERS OF THE SOUTHERN ATLANTIC STATES AND THEIR TREATMENT. JAMA. 1896;XXVII(26):1319–1325. doi:10.1001/jama.1896.02431040001001
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