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July 6, 1895


JAMA. 1895;XXV(1):34. doi:10.1001/jama.1895.02430270050005

Among the more recent applications of serotherapy is that of treating infections of the streptococci with the serum of animals immunized against the microbe which—as comprehensively summarized by a French contemporary1—causes phlegmon, erysipelas and puerperal fever; which induces suppuration in cellular tissue, as in serous cavities; which is always present in the mouth and pharynx; which may, in short, give rise to a series of affections ranging from simple angina to peritonitis and which, moreover, complicates nearly all infectious diseases, both acute and chronic. To successfully combat this terrible adversary would be to give aid of extraordinary power to the physician, the surgeon and the accoucheur. It is this aid which various observers, especially Roger and Charrin, Marmorek and Chantemesse hope to have discovered in anti-streptococcic serum. Mironoff first and then Charrin and Roger began by immunizing animals against the streptococci and,by injecting five or six cubic centimeters