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February 27, 1904


JAMA. 1904;XLII(9):595-596. doi:10.1001/jama.1904.02490540027005

Albuminuria in small amount may appear inconstantly in the urine under so many varied circumstances that its discovery fails to arouse the concern that otherwise it would. Nevertheless, the underlying cause should, so far as possible, be sought out and corrected. The mere presence of albumin in the urine, without other evidence of disease of the kidneys or their adnexa, may be considered a functional disturbance indicative of renal insufficiency, which, in itself, may be attended with no injurious effects, but whose existence should raise a question as to the vulnerability of the organs concerned. In order, therefore, to avert more serious disorder, the urine should be examined with systematic regularity, both chemically and microscopically.

The qualification physiologic, as applied to albuminuria, does not seem entirely appropriate, as the fact of the condition being the exception rather than the rule indicates the contrary. There has also been described a form