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April 7, 1906


JAMA. 1906;XLVI(14):1021-1022. doi:10.1001/jama.1906.02510410023006

It is not my wish to call your attention to any new chemical product of coal tar nor to any of the modern medicinal agents that are guaranteed to cure all diseases, but rather to refresh your memories as to some old and, to myself at least, new properties of one of the oldest agents in the materia medica.

The history of the use of lupulin as a medicinal agent dates back as far as the oldest medical literature. Up to the early part of the last century it was used for almost every pain or disease. Before the discovery of the iodid it was considered almost a specific for scrofula, struma and the various skin diseases. In 1852 it was resurrected by the surgeons of the French genitourinary school, and then for the first time came under the critical eye of modern clinical observation. After a few years of

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