The therapeutic application of antiphthisin has thus far been limited to comparatively few practitioners, partly on account of limited production, and partly because the remedy was only furnished to such as gave us assurance that they would restrict its application to cases which were not too far advanced in the disease, and in which we could still hope for its beneficial effects.
The reason for restriction is apparent by the well-known fact that specific medication can only be fully effective, when it is applied to pure uncomplicated cases, to the exclusion of those in which other pathologic processes are also present.
It would certainly be unreasonable to demand that this remedy which has a specific germicidal effect upon the tubercle bacillus only, shall also remove and cause the cure of pathologic changes, which result remotely from the primary cause and, more unreasonable still, that the remedy shall also favorably influence
KLEBS E. ANTIPHTHISIN IN TUBERCULAR AFFECTIONS OF CHILDREN. JAMA. 1895;XXV(15):601–606. doi:10.1001/jama.1895.02430410001001
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