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The frequency of eye disease originating from brain lesion is all sufficient to render an attempt to trace a closer relationship between the eyes and the brain justifiable and merits, by reason of its utility in ocular and brain diagnoses, very careful consideration. If we are dealing with structural ocular changes we are often able to define the etiologic factor at once, but at times we are confronted by functional disturbances which are but vaguely explicable; under such circumstances if we could only view the eyes as a component factor of the cerebral and cerebellar mechanism, obscurity in diagnosis would vanish. I have always regarded the eyes as nothing more nor less than prolonged bulbous expansions of the optic nerves with altered anatomic characters to meet the requisites of their physiologic necessity, viz., to formulate and receive impressions of the external world and, carrying the analogy a step further, we
LYDSTON JA. THE RELATIONSHIP BETWEEN THE EYES AND THE BRAIN. JAMA. 1895;XXV(19):792–793. doi:10.1001/jama.1895.02430450008001d
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