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April 2, 1904

Effect of Potassium Iodid on Urine.

JAMA. 1904;XLII(14):906. doi:10.1001/jama.1904.02490590040017

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Philadelphia, March 22, 1904.

To the Editor:  —The following case is reported as a clinical note, not because it presents new or unusual features, but because it brings into question the propriety of a very common method of administration of one of our most commonly used drugs, and also because the reaction obtained in a specimen of the urine may not be familiar to all of your readers. The urine referred to was from a young tuberculous subject, whose case was observed in the Methodist Hospital in Philadelphia. The resident physician, Dr. Richmond, noted that on boiling the urine and adding a small quantity of nitric acid the fluid first assumed a deep claret color, and later, on the further addition of acid, a purplish tint which colored the foam and the fumes a brilliant purple also. At first it was suspected that the reaction was one to which attention

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