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During the past two decades, or the last quarter of the nineteenth century, a vast change has been wrought in the principles governing surgical operations; the use of the microscope has sapped the very foundations of pathology which was taught as late as the early 70's, and in that short space of time, we have witnessed the birth and death of many theories which were advanced with the force of dogmatic emphasis.
In short, our age is one of theories and it would seem that in spite of the scientific foundation which modern medicine is supposed to rest on, our position is anything but fixed and definite, and, never, probably at any time, was the profession more eager to test the efficacy of any therapeutic agency, provided only that its source was from those recognized as authorities. Our bent is essentially materialistic, and we are endeavoring to wring from nature
MANLEY TH. THE LIMITATIONS OF SURGICAL OPERATIONS AS A MEANS OF RELIEF OR CURE IN EPILEPSY. JAMA. 1895;XXV(24):1017–1020. doi:10.1001/jama.1895.02430500003001b
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