One fine morning, some weeks ago, a young lady, an actress by profession, came to consult me about an obstinate headache. "I have used everything you can think of," she said. "I have used antikamnia, Kohler's headache powders,—'s migraine tablets, orangeine, Hegeman's headache wafers and a lot of other things. At first they used to relieve me, but now they don't do me any good." The self-drugging young woman enumerated five different articles which she had used; different articles in name, but identically the same so far as composition is concerned. Everyone of those articles consists of acetanilid, sodium bicarbonate and a little caffein. Finding a malarial history, I prescribid quinin and ergotin, and her headaches promptly vanished.
About two weeks later a young practitioner approached me at the close of a medical meeting with the following words : "Doctor, I wish you would recommend me something good for dysmenorrhea.
ROBINSON WJ. THE COMPOSITION OF SOME SO-CALLED SYNTHETICS AND "ETHICAL" NOSTRUMS. JAMA. 1904;XLII(16):1016–1020. doi:https://doi.org/10.1001/jama.1904.92490610021002g
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