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April 23, 1904


JAMA. 1904;XLII(17):1084. doi:10.1001/jama.1904.02490620026011

"Antitrope," or "antitropin," is a new term which Wright2 has invented as a generic term for the antibodies. Aside from the fact that it is undesirable to introduce a multiplicity of terms to designate the same thing, we are inclined to consider the word itself a poor one. The use of anti- is appropriate in two senses; it expresses, in the first place, the antagonism which an antibody has for its counter-substance, and suggests also the general law that by immunizing with proper proteid bodies there are developed new bodies the specific opposites of those injected. The term antibody seems, then, to express the important qualities in a generic sense. The addition of -trope or -tropin (from the Greek (unk), to turn) introduces the idea of affinity into a word which already bears the meaning of antagonism. Either root may be considered as appropriate, but the two combined add