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February 1, 1896

Poisoning by Acetanilid.

JAMA. 1896;XXVI(5):239-240. doi:10.1001/jama.1896.02430570041008

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Quincy, Ill, Jan. 19, 1896.

To the Editor:  —In our Journal of Jan. 18, 1896, page 144, reference is made to a report in the Virginia Medical Monthly, by Dr. Ben. H. Broadnax, on the use of acetanilid. Having recently had in my own practice two cases of acetanilid poisoning, one terminating fatally, I can not, therefore, indorse Dr. Brodnax's recommendation for the use of this drug, particularly in new-born infants. A few weeks ago I prescribed for a babe of four days, suffering with ah erythematous inflammation of the skin of the nates, thighs and groins, a powder composed of equal parts of subnitrate of bismuth and acetanilid. During that afternoon and night the powder was dusted upon the inflamed areas three or four times. On the following morning the babe was found deeply cyanosed, and died a few hours later.Before realizing that acetanilid was the cause of

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