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According to Hugh M. Taylor, 50,000 to 75,000 deaths occur annually in the United States from typhoid fever. If this is correct, and if we accept Osler's statement that one-third of these deaths are due to intestinal perforation, we have, at the lowest estimate, 16,666 deaths annually in the United States due to typhoid perforation. Again, accepting the opinion of Osler, Finney and others who have had the most experience with this condition, that one-half of these lives might be saved by timely operation, we have a grand total of 8,333 persons annually whose lives might be saved by timely surgical intervention. The average age of those dying from typhoid fever is 28.8 years, the greater number being males, most of them the heads of families. If, by carrying out the ideal treatment, 8,333 persons in the most valuable period of life might be saved to their families and to
DAVIS BB. INTESTINAL PERFORATION IN TYPHOID FEVER.. JAMA. 1904;XLII(21):1329–1332. doi:10.1001/jama.1904.92490660001001
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