[Skip to Content]
[Skip to Content Landing]
May 21, 1904


JAMA. 1904;XLII(21):1336-1343. doi:10.1001/jama.1904.92490660008001c

The publication of an article of this general nature1 seems justifiable, in order to extend familiarity with a phase of medical progress, which is nothing less than epochal in its achievements. It is also desirable that we appreciate the nature and degree of permanence of the results so far obtained in serum therapy, its present range of application and limitations, and the underlying principles of the successes and failures insofar as they are understood, in order that we may hold ourselves in a proper state of receptivity for results which the future is likely to provide.

The most distinctive features, medically and surgically, of the period in which we find ourselves, have developed from the knowledge of microbic etiology of the infectious diseases. Among the consequences of this knowledge, one of the most important is that the body, in the presence of an infection, has the power to produce specific