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April 11, 1896

Uric Acid as a Factor in the Causation of Disease, a contribution to the pathology of high arterial tension, headache, epilepsy, mental depression, paroxysmal hemoglobinuria and anemia, Bright's disease, diabetes, gout, rheumatism, etc.

JAMA. 1896;XXVI(15):737. doi:10.1001/jama.1896.02430670039015

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This book which has now reached its third edition contains a vast amount of information upon the physiology of the production and elimination of uric acid and urea, and the pathologic changes caused by the retention of these excrementitious substances. The relations between certain forms of headache, mental depression, Raynaud's disease, rheumatism and uric acid are so clearly set forth with mathematical accuracy.

The author was himself a sufferer from the gouty diathesis, and has learned to control it practically by a suitable vegetarian and non-alcoholic dietary.

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