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Article
October 20, 1906

THE SIMULTANEOUS OCCURRENCE OF TWO NON-RELATED TUMORS IN A MOUSE.

Author Affiliations

Director of Cancer Research, Harvard Medical School. BOSTON.

JAMA. 1906;XLVII(16):1237-1241. doi:10.1001/jama.1906.25210160001001
Abstract

HISTORY OF THE CASE.  The tumors described in the present paper occurred in an old uninoculated mouse kept apart for breeding purposes. They were primary in the lung and in the kidney.

History.  —The mouse was an old, black, female, purchased April 29, 1905. It died Aug. 4, 1905. During this time, slightly over three months, it raised two litters of young and was vigorous and apparently in good health up to the last week of its life. At this time the two young ones, which were then about three weeks old, appeared small and poorly nourished, but were soon able to care for themselves. The mother ate irregularly and became uneasy. There was a slight loss of flesh and toward the last the animal's breathing became labored. An autopsy was made immediately after death.

Autopsy.  —The superior lobe of the right lung occupies the major portion of the right

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