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Dr. Paul Marie of Paris, in 1886, gave to the medical world a classic description of certain rare pathologic conditions and appearances to which, though noted possibly for many years, he gave the name Acromegaly, thus adding to medical nomenclature a new word. This word is a combination of two Greek words, meaning enlarged extremity. But the term is elastic enough to cover more territory than just what its root words signify, so that in general, acromegaly may be defined as a symmetrical enlargement of the extremities and face.
Reported cases studied to the present time apparently fix five facts, viz., that hereditary influences cut no figure in causation; that the disease usually appears between 12 and 30 years of age; preponderates in males; that theorists are at sea as to the causes, and that all treatment up to date is unavailing.
To account for the simultaneous and abnormal growth
RATHMELL JR. ACROMEGALY—WITH A CASE. JAMA. 1897;XXVIII(12):540–542. doi:10.1001/jama.1897.02440120014002e
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