Our knowledge of the functions of the cerebrum has been obtained from studies of the effects of stimulation and destruction of the various parts of the organ. In this study both physiologists and clinicians have been engaged. Physiologists have spent most time in determining the effects of lesions, experimentally produced, and the motor accompaniments of stimuli of different kinds. The clinicians, including surgeons, neurologists and pathologists, have been able to observe in man the effects of destructions from accidents, disturbances of functions from emboli, thrombi and hemorrhages, and in some cases it has been found practicable to stimulate the cerebral cortex in man after the fashion of the physiologic experiments and thus to map out the muscular reactions represented in the cortex.
PHYSIOLOGIC AND CLINICAL METHODS.
Both the physiologic and the clinical methods have advantages and disadvantages. On animals the physiologist is enabled to limit the lesion, to repeat his
FRANZ SI. OBSERVATIONS ON THE FUNCTIONS OF THE ASSOCIATION AREAS (CEREBRUM) IN MONKEYS. JAMA. 1906;XLVII(18):1464–1467. doi:10.1001/jama.1906.25210180040001j
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