While the remedy of which I shall speak is not new to me, it is new to the larger part of the profession. Methylene blue was introduced into practice in malignant tumors by Moorhof-Mosetig of Vienna. I believe the first man who introduced it into America was Willy Meyer of New York. At that time I used it a good deal by the injection method. The injections are very painful and inadmissible because it is impossible to prevail on any patient to submit to them for any length of time. Therefore, for fourteen or fifteen years, I have given methylene blue, or as it is now called, methylthionin hydrochlorid, in my own way internally.
WHEN TO USE IT.
As a rule we see cancer in an advanced state. Small cancers, local cancers, will very frequently go into the hands of the surgeons where they belong and the operation is certainly
JACOBI A. METHYLTHIONIN HYDROCHLORID IN INOPERABLE CANCER. JAMA. 1906;XLVII(19):1545–1546. doi:10.1001/jama.1906.25210190025001j
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