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November 10, 1906


JAMA. 1906;XLVII(19):1569. doi:10.1001/jama.1906.02520190049011

There are few affections with which mumps is likely to be confounded, but at times, especially at an early stage of the disease, and when a definite diagnosis is at once required, a ready means of recognition is much to be desired. It has been shown that characteristic changes in the blood take place even during the first days of an attack of mumps, and this fact may be utilized practically as a means of diagnosis. The number of leucocytes is, as a rule, increased, although the leucocytosis may not be marked. There is a noteworthy increase in the number of lymphocytes and a somewhat proportionate diminution in the number of polymorphonuclear neutrophiles. Observations yielding parallel results have been made by Dr. Ira S. Wile,1 who has found the lymphocytosis, both relative and absolute, constant, appearing on the first day of the disease and persisting until the glandular swelling has