During the last few years the subject of hypernephroma has received a thorough consideration by a number of careful observers. Special phases of the subject have received special emphasis. When cases are reported, reference is always made to the question of secondary manifestations. It is a question, however, which presents a number of interesting features, and for that reason we have given it considerable thought.
Mention is frequently made of the rarity of this tumor formation; this, however, is a mistake. On the other hand, the pathologist who carefully examines all specimens brought to him finds them of rather frequent occurrence.
A hypernephroma is a tumor consisting of adrenal structure and having its origin from suprarenal gland, or from particles of this gland which have become displaced, the displacement of tissue being usually into the kidney or under its capsule. Misplacement of tissue elements often takes place during the period
BIERRING WL, ALBERT H. SECONDARY MANIFESTATIONS OF HYPERNEPHROMATA. JAMA. 1904;XLIII(4):234–239. doi:10.1001/jama.1904.92500040002
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