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December 1, 1906

THE ROLE OF NUCLEIN IN THE ANIMAL ECONOMY.WITH A STUDY OF URIC AND PHOSPHORIC ACID EXCRETION IN ONE HUNDRED AND TWENTY-NINE CASES.

Author Affiliations

Professor of Medicine in Indiana Medical College, Medical Department of Purdue University. FORT WAYNE, IND.

JAMA. 1906;XLVII(22):1800-1804. doi:10.1001/jama.1906.25210220026001e
Abstract

The motive for presenting this clinical study was found in some statements coming from respectable but forgotten quarters of current medical literature to the effect that the excretion of uric and phosphoric acids rose and fell together, statements contrary to my own observations. While I soon found that the simple refutation of these careless propositions would be very much like setting up a man of straw for the pleasure of knocking it over, yet the absolute and relative excretions of these final products of metabolism, under average conditions of diet in chronic nutritional disease, seemed to me to be of both practical and scientific interest. I therefore asked my assistant to glean from my notes the necessary data from about one hundred unselected cases. The result, as shown in the appended table, was 192 analyses in 129 cases, comprising 36 different diseases. With reference to the exact diagnosis of these

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