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Article
December 15, 1906

CASE OF MULTIPLE FIBROSARCOMA OF THE TONGUE, WITH REMARKS ON THE USE OF TRYPSIN AND AMYLOPSIN IN THE TREATMENT OF MALIGNANT DISEASE.

JAMA. 1906;XLVII(24):2003-2008. doi:10.1001/jama.1906.25210240037001j
Abstract

Primary sarcoma of the tongue is a disease so seldom met or recognized and recorded that a case of this character presents features of unusual interest. There appear to be less than forty well authenticated cases on record. Of the various varieties of sarcoma invading this organ, the fibrous seems the least frequent, as only three or four of the cases just mentioned are classified under this head.

History.  —N. M., an unmarried female, aged 23, of Irish descent, a domestic, applied in November, 1905, to the Metropolitan Nose and Throat Hospital for treatment, complaining of an enlargement of the back of her tongue, which was causing her much discomfort, as, on account of its size, it made speaking, eating and sleeping difficult. The patient then stated that she had asked for treatment at several hospitals in London, but had been refused operation.She was referred to me as one

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